The Decree-Law no.115/2010, of October 22 where the Directive 2007/60/EC of the European Parliament and of the Council of 23 October 2007 on the assessment and management of flood risks is transposed into Portuguese national law, establish a framework for the assessment and management of flood risks.Flash floods and debris events have a long histor
Polymer nanoparticles modified with collagen peptides (CPs) are an attractive strategy for the oral delivery of active ingredients from Chinese medicine.Thus, in the present study, collagen cationic CPs were simply separated using ion-exchange resin from bovine CPs, to modify mixed nanomicelles (MMs) on the surface to improve the oral bioavailabili
Obtaining accurate quantitative measurements in preclinical Positron Emission Tomography/Computed Tomography (PET/CT) imaging is of paramount importance in biomedical research and helps supporting efficient translation of preclinical results to the clinic.The purpose of this study was two-fold: (1) to investigate the effects of different CT acquisi
The depth and versatility of siRNA technologies enable their use in disease targets that are undruggable by small molecules or Specialty Pipes that seek to achieve a refined turn-off of the genes for any therapeutic area.Major extracellular barriers are enzymatic degradation of siRNAs by serum endonucleases and RNAases, renal clearance of the siRNA
balance bikes In this paper, by applying the Jacobian ellipse function method, we obtain a group of periodic traveling wave solution of coupled KdV equations.Furthermore, by the implicit function theorem, the relation between some wave velocity and the solution’s period is researched.Lastly, we show that this type of solution is orbitally stable